Learning Objectives

At the end of the 2025 CRS Annual Meeting, participants will be able to:

1

Describe the utility of the latest imaging modalities in the management of challenging medical and surgical retinal disorders

2

Describe novel technological advances in vitreoretinal surgery

3

Provide an update on the latest advances in the management of medical retinal conditions with a focus on new and emerging generations of therapeutic agents

4

Provide an update on recent advances in the management of Retinopathy of Prematurity and other medical and surgical pediatric retinal condition

Agenda

Friday, April 25, 2025

PLENARY SESSION #1 – SURGERY
Regency Ballroom C 3rd Floor
Moderators: Keyvan Koushan, MD and Bernard Hurley, MD

3:30 PMWelcome and Opening Remarks
Keyvan Koushan, MD and Bernard Hurley, MD
3:40 PMCanadian Conundrums: Surgical Session & Discussion
Amin Kherani, MD
4:40 PMViscodissection for Tractional Retinal Detachments
Rishi Singh, MD
4:51 PMUsing Pre-Operative Circumpapillary RNFL OCT as a “Treasure Map” to Plan and Facilitate PVD Creation in Vitreoretinal Surgery
David Brown, MD
5:02 PMInferior Retinal Break Rhegmatogenous Retinal Detachment (IRB-RRD)
Noemi Lois, MD, PhD
5:12 PMQ&A
6:00 PMWelcome Reception – English Bay 34th Floor

Saturday, April 26, 2025

7:00 AMBreakfast – Regency Ballroom E/F 3rd Floor

PLENARY SESSION #2 – SURGERY
Regency Ballroom C 3rd Floor

8:30 AMNew Concepts in the Understanding of ERM Pathogenesis
David Sarraf, MD
8:41 AMPars Plana Vitrectomy – Suprachoroidal Viscopexy (VIT-SCVEXY) for Rhegmatogenous Retinal Detachment Repair
Aurora Pecaku, MD
8:50 AMMinimally-Invasive Suprachoroidal Buckling Using a Novel Injector: Pre-Clinical Evaluation in Human Cadaver Eyes
Gareth Mercer, MD, PhD
8:59 AMPneumatic Retinopexy Prior to Pars Plana Vitrectomy for Rhegmatogenous Retinal Detachments – the “Bubble and Book”
Jess Xiong, MD
9:08 AMRD in Cavitary Disc Anomaly
Wei-Chi Wu, MD, PhD
9:19 AMComparison of Outcomes Between Idiopathic Macular Holes versus Bacillary Layer Detachment-Lamellar Holes in Rhegmatogenous Retinal Detachments
Isabela Martins Melo, MD
9:28 AMRefractive and Clinical Outcomes of Secondary Intraocular Lens Surgery between Intra-scleral Haptic Fixation (Yamane) Technique versus Gore-Tex Sutured EnVista Lenses
Bryon McKay, MD, PhD
9:37 AMQ&A
10:00 ‒ 10:45 AMSATELLITE SYMPOSIUM
10:45 ‒ 11:10 AMBreak – Poster Session – Regency Ballroom C/Balmoral 3rd Floor

PLENARY SESSION #3 – SURGERY
Regency Ballroom C 3rd Floor

11:10 AMIntroduction to the Mila Oh Memorial Lecture
11:15 AMMila Oh Memorial Lecture: Proliferative Diabetic Retinopathy: From Risk Factors to Treatment Selection
Noemi Lois, MD, PhD
11:26 AMFloaterectomy Surgery – Good, Bad, and Ugly
Rishi Singh, MD
11:37 AMComparative Analysis of Intraocular Pressure Changes in Pneumatic Retinopexy Versus Vitrectomy for the Treatment of Retinal Detachments
Sue Ellen Demian, MD
11:46 AMImpact of Baseline Morphologic Stage of Full-Thickness Macular Hole on Postoperative Visual Acuity
Aurora Pecaku, MD
11:55 AMLate Complications of Regressed ROP: RD, VH, and Retinal Breaks
Wei-Chi Wu, MD, PhD
12:06 PMQ&A
12:30 PMLUNCH – Regency Ballroom E/F 3rd Floor
1:30 – 2:15 PMSATELLITE SYMPOSIUM

PLENARY SESSION #4 – AI and Retinal Imaging 
Regency Ballroom C 3rd Floor

2:30 PMSignature OCT 2025: New Diseases and Novel Findings
David Sarraf, MD
2:41 PMAreas of Hypofluorescent Delayed Near InfraRed Analysis (DNIRA) Precede Areas of Hypofluorescent Blue FAF in a Prospective, Longitudinal Study of Eyes with Multifocal Geographic Atrophy (GA) Due to Age-Related Macular Degeneration (AMD)
Shelley Boyd, MD
2:50 PMGenerative-AI for Dye-Free Fluorescein Angiography
Alan Cruess, MD
2:59 PMOral vs IV FA in ROP
Wei-Chi Wu, MD, PhD
3:10 PMQ&A
3:35 – 4:20 PMSATELLITE SYMPOSIUM
4:20 – 5:10 PMBreak – Poster Session – Regency Ballroom C/Balmoral 3rd Floor
5:15 – 6:00 PMCRS Annual General Meeting
6:30 PMGALA – Regency Ballroom A/B 3rd Floor

Sunday, April 27, 2025

7:00 AMBreakfast - Regency Ballroom E/F 3rd Floor

PLENARY SESSION #5 – AI and Retinal Imaging 
Regency Ballroom C 3rd Floor

8:35 AMOCTA of Macular Disease: Can It Improve Clinical Care?
David Sarraf, MD
8:46 AMERM Macular Leakage
David Wong, MD
8:55 AMOphthoACR: A Novel AI-Driven Tool for Automating Ophthalmology Chart Review and Data Extraction
Vlad Diaconita, MD
9:04 AMQ&A
9:15 – 10:00 AMSATELLITE SYMPOSIUM
10:00 – 10:20 AMBreak / Poster Session – Regency Ballroom C/Balmoral 3rd Floor

PLENARY SESSION #6 – Medical Retina 
Regency Ballroom C 3rd Floor

10:25 AMDrug Clearance Variability Explains Why Many Patients Need More Frequent Intravitreal Injections Despite “Longer-Acting” Agents
David Brown, MD
10:36 AMSubretinal Delivery of Investigational ABBV-RGX-314 as a Gene Therapy for Neovascular Age-Related Macular Degeneration (nAMD): Interim Results of Bilateral Dosing from a Fellow Eye Study
Raman Tuli, MD
10:47 AMVisual and Anatomic Outcomes of Dual Inhibition in Naïve nAMD Patients with Associated Subretinal Hemorrhage
Nirojini Sivachandran, MD, PhD
10:56 AMBaseline Ellipsoid Zone Integrity Features as Predictors of Geographic Atrophy Growth Rate in the Phase 3 GATHER Clinical Trials
Varun Chaudhary, MD
11:05 AMDiabetic Macular Edema (DME): A Personalized Treatment Approach
Noemi Lois, MD, PhD
11:14 AMQ&A

PLENARY SESSION #7  - Medical Retina 
Regency Ballroom C 3rd Floor

11:30 AMTyrosine Kinase Inhibitors for AMD and DME/DR
Rishi Singh, MD
11:41 AMFinal Results and Exploratory Outcomes of the HORNBILL Study: A Phase I/IIa Trial of BI 764524 in Patients with Diabetic Macular Ischemia
Varun Chaudhary, MD
11:50 AMThe 3 Drug Problem: Cost-Analysis of an “Avastin Preferred” Vial Splitting Program in Alberta, Canada for Vitreoretinal Diseases Treated with anti-VEGF Therapy
Amin Kherani, MD
11:59 AMQ&A
12:10 PMConcluding Remarks
Co-chairs: Bernard Hurley, MD, and Keyvan Koushan, MD
12:30 PMLunch – Regency Ballroom E/F 3rd Floor
Please check back soon.

Annual Meeting Agenda

All Sessions: Cinema - Ground Floor

Note: this meeting will take place in English.

Guest Speakers:

Robyn Guymer, AM, MBBS, PhD, FRANZCO, FAHMS
Professor of Ophthalmology
Melbourne University
Deputy Director
Centre for Eye Research Australia
Melbourne, Victoria, Australia
Sobha Sivaprasad, MBBS, FRCS, FRCOphth
Medical Retina Consultant Ophthalmologist
Moorfields Eye Hospital NHS Foundation Trust
Professor in Retinal Clinical Research
University College London
London, United Kingdom
Carl D. Regillo, MD, FASRS
Professor of Ophthalmology
Thomas Jefferson University
Chief, Retina Service, and Founder
Wills Eye Clinical Retina Research Unit, Wills Eye Hospital
Sunil K. Srivastava, MD
Staff Physician
Cole Eye Institute, Cleveland Clinic
Cleveland, Ohio

Friday, May 12

PLENARY SESSION #1COAST-TO-COAST RETINA CHECKUP PART 1 SURGERY
Moderators: Bernard Hurley, MD, and Robert Gizicki, MD

3:30 pm Welcome and Opening Remarks

3:40 pm Vitreoretinal Surgical Video Session: “Masters of Disasters”
David Wong, MD
Q&A (included)

4:25 pm Vitreoretinal Surgery in Uveitis
Sunil Srivastava, MD

4:40 pm  Q&A Session

4:45 pm Pearls in Pediatric Retina Surgery
Cynthia Qian, MD

4:51 pm Complex Vitreoretinal Surgery
Flavio Rezende, MD, PhD

4:57 pm Bacillary Layer Detachment in the Pathophysiology of Secondary Macular Hole in Fovea-off Rhegmatogenous Retinal Detachment
Isabela M. Melo, MD

5:03 pm Q&A

5:11 pm Efficacy and Safety of Proposed MYL-1701P Biosimilar Compared to Eylea® (Reference Aflibercept) in Diabetic Macular Edema: A Randomized, Double-masked, Phase 3 Equivalence Study (INSIGHT Study)
Susan B. Bressler, MD

5:17 pm 2-Year Evaluation of Subretinal Fluid Drainage Techniques in Pars Plana Vitrectomy for Primary Rhegmatogenous Retinal Detachment
(ELLIPSOID-2 Study)
Aditya Bansal, MD

5:23 pm Lenses for Pars Plana Scleral Fixation
Amar Mannina, MD

5:29 pm Q&A

5:37 pm Session 1 Concluding Remarks
Moderators: Bernard Hurley, MD, and Robert Gizicki, MD

6:00 pm Welcome Reception - Princes' Gates Ballroom

Saturday, May 13

7:00 am BREAKFAST – Princes’ Gates Ballroom

7:30 am SATELLITE SYMPOSIUM – Cinema Ground Floor

PLENARY SESSION #2 – AGE-RELATED MACULAR DEGENERATION & DIABETIC MACULAR EDEMA
Moderators: Varun Chaudhary, MD, and Jason Noble, MD

8:30 am Introduction to Section 2

8:40 am Reticular Pseudodrusen – A Critical Phenotype
Robyn Guymer, AM, PhD

8:55 am Q&A

9:02 am Tyrosine Kinase Inhibition for nAMD Clinical Trial Studies
Carl Regillo, MD

9:17 am Q&A

9:24 am Early OCT Signs of Atrophy in AMD
Robyn Guymer, AM, PhD

9:39 am Q&A

9:46 am Translating Clinical Trials to Practice in Geographic Atrophy
Sobha Sivaprasad, MBBS

10:01 am Q&A

10:08 am VOYAGER: An Innovative Real-world Study of Faricimab and the Port Delivery System with Ranibizumab in Patients with nAMD and DME
Robyn Guymer, AM, PhD

10:23 am Q&A

10:30 am BREAK – Princes’ Gates Ballroom Pre-function Area, 3rd Floor
Poster Session

 

PLENARY SESSION #3 – Retinal Vascular Disease
Moderators: Bernard Hurley, MD, and Robert Gizicki, MD

11:00 am Introduction to Session 3

11:05 am Choice of Agent in CRVO
Sobha Sivaprasad, MBBS

11:15 am Q&A

11:22 am CRAO Management and CRAO Masquerades
Sunil Srivastava, MD

11:37 am Q&A

11:44 am Where Do We Place Biosimilars in Our DME Treatment Algorithm?
Sobha Sivaprasad, MBBS

12:00 pm Q&A

12:07 pm Discontinuous Versus Continuous Treatment for DME: Evidence Review and Evidence Generation
Varun Chaudhary, MD

12:22 pm Q&A

12:30 pm LUNCH – Princes’ Gates Ballroom

1:15 pm SATELLITE SYMPOSIUM – Cinema Ground Floor

 

PLENARY SESSION #4 – Surgery
Moderator: Bernard Hurley, MD, and Wai-Ching Lam, MD

2:15 pm Introduction to Session 4

2:20 pm Perfluorocarbon Liquid in Retinal Detachment Repair: Pearls and Pitfalls
Carl Regillo, MD

2:35 pm Q&A

2:42 pm Mila Oh Memorial Lecture: Diagnosis and Management of Diabetic Retinopathy in 2030
Sobha Sivaprasad, MBBS

2:57 pm Q&A

3:04 pm The Surgical Management of Inherited Retinal Diseases
Peter Kertes, MD

3:19 pm Q&A

3:26 pm Gene Therapy for Neovascular AMD and Diabetic Retinopathy
Carl Regillo, MD

3:41 pm Q&A

3:48 pm BREAK – Princes’ Gates Ballroom Pre-function Area, 3rd Floor
Poster Session

 

PLENARY SESSION #5 – Uveitis
Moderators: Phil Hooper, MD, and Robert Gizicki, MD

4:15 pm Introduction to Session 5

4:25 pm Masquerade Syndromes, New Treatment in Uveitis Imaging
Sunil Srivastava, MD

4:40 pm Q&A

4:47 pm Clinical and Imaging Pearls in Uveitis
Nupura Bakshi, MD

5:02 pm Q&A

5:15-6:00 pm CRS Annual General Meeting – Cinema Ground Floor

6:30 pm GALA – Princes’ Gates Ballroom

Sunday, May 14

7:30 am BREAKFAST

PLENARY SESSION #6 – Coast-to-Coast Part 2 Medical Retina
Moderators: Bernard Hurley, MD, and Robert Gizicki, MD

8:45 am Introduction to Session 6

8:50 am Pachychoroid Spectrum Diseases
Wai-Ching Lam, MD

8:56 am Scleral Buckle Techniques
Geoff Williams, MD

9:02 am Exciting and New
Mark Greve, MD

9:08 am Does Anti-VEGF Treatment Impact Retinal Nonperfusion in Diabetic Retinopathy?
Varun Chaudhary, MD

9:14 am Q&A

9:30 am SPONSORED SYMPOSIUM – Cinema Ground Floor

10:30 am BREAK – Trillium Park Studio, 3rd Floor
Poster Session

10:45 am Assessment of Geographic Atrophy Progression in the Phase 3 OAKS and DERBY Trials
Tom Sheidow, MD

10:51 am Retinal Displacement After Scleral Buckle Versus Combined Buckle and Vitrectomy for Rhegmatogenous Retina Detachment: ALIGN SB vs PPV-SB
Aditya Bansal, MD

10:57 am The Long-term Structural and Functional Impact of Retinopathy of Prematurity
Cynthia Qian, MD

11:03 am Delayed Near InfraRed Analysis (DNIRA) Identifies Novel Features of Nonexudative (Dry) AMD in a Prospective, Natural History Study
Filiberto Altomare, MD

11:09 am Q&A

11:24 am Concluding Remarks
Co-chairs: Bernard Hurley, MD, and Robert Gizicki, MD

12:00 pm LUNCH – Princes’ Gates Ballroom

Poster Presenters

Isabela M. Melo, MD – Toronto, ON

  • Posterior Hyaloid Discontinuity on Optical Coherence Tomography in Partial Posterior Vitreous Detachment and Vitreomacular Traction
  • Impact of Baseline Morphological Stage on Post-operative Outcomes in Rhegmatogenous Retinal Detachment

Parnian Arjmand, MD – Toronto, ON

  • Juxtafoveal Retinal Arterial Macroaneurysm: The Role of Ancillary Imaging

Amin Kherani, MD – Calgary, AB

  • Intraocular foreign body injuries from a Calgary perspective – a retrospective case series

Carl Shen, MD – Hamilton, ON

  • Intraretinal silicone oil migration: An under recognized OCT phenotype

Paola Oquendo, MD – Hamilton, ON

  • Comparison of the Photoreceptor Mosaic Before and After Macular Hole Surgery with High Resolution Adaptive Optics Imaging
  • Epiretinal Membrane and Associated Tractional Abnormalities Following Rhegmatogenous Retinal Detachment Repair

Hatim Batawi, MD – Toronto, ON

  • Outer Retinal Hyperreflective Dots, A Potential Biomarker in Rhegmatogenous Retinal Detachment

Khaldon Abbas – Vancouver, BC

  • Characteristics of No-show appointments at a multicenter retina subspeciality practice

Aurora Pecaku, MD – Toronto, ON

  • Reattachment Rate with Pneumatic Retinopexy vs Pars Plana Vitrectomy for Rhegmatogenous Retinal Detachment with a Single Break in Detached Retina Only

Irina Sverdlichenko – Toronto, ON

  • Macular Hole Associated Retinal Detachment in High Myopic Patients: Case series and Overview of a Novel Surgical Technique

Aaditeya Jhaveri – Toronto, ON

  • Optical coherence tomography biomarkers as potential predictors for visual function and response to intravitreal therapy in diabetic macular edema: a review

Fowad Daud – Hamilton, ON

  • Combined versus Sequential Pars Plana Vitrectomy and Phacoemulsification for Macular Hole and Epiretinal Membrane – A Systematic Review and Meta-Analysis

Milena Cioana – Toronto, ON

  • Post-procedural endophthalmitis visual outcomes by microorganism: A systematic review and meta-analysis
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