Learning Objectives

At the end of the 2024 CRS Annual Meeting, participants will be able to:

1

Describe the utility of advanced imaging modalities in assisting with the management of challenging medical and surgical retinal disorders

2

Describe novel technological advances in vitreoretinal surgery

3

Provide an update on the latest advances in the management of medical retinal conditions with a focus on the new complement inhibitors for dry macular degeneration

4

Provide an update on recent advances in the management of medical and surgical pediatric retinal conditions

Agenda

Friday, May 3, 2024

PLENARY SESSION #1 – SURGICAL VIDEOS & PEDIATRICS: ENDLESS CHALLENGES

3:30 ‒ 3:40 PMWelcome and Opening Remarks
3:40 ‒ 4:35 PMCanadian Conundrums – Surgical Video Session
David Wong, MD; Amin Kherani, MD
4:40 ‒ 4:48 PMApproaches to Anterior and Posterior Persistent Fetal Vascular Syndrome in Infants
Philip Ferrone, MD
4:48 ‒ 4:54 PMQ&A
4:55 ‒ 5:03 PMChallenging Pediatric Surgical Cases
Cynthia Qian, MD
5:03 ‒ 5:09 PMQ&A
5:11 ‒ 5:19 PMPediatric Macular Hole
Philip Ferrone, MD
5:19 ‒ 5:30 PMQ&A
6:00 PMWelcome Reception

Saturday, May 4, 2024

7:00 AM Breakfast

PLENARY SESSION #2 – SURGERY

8:30 ‒ 8:40 AMThe Retina Foundation of Canada: An Introduction
John Galic, MD
8:40 ‒ 8:48 AMPossibilities for Robotics in Retinal Surgery in the Future
Lyndon da Cruz, MD, PhD
8:48 ‒ 8:53 AMIntroduction to Mila Oh Memorial Lecture
8:54 ‒ 9:02 AMMila Oh Memorial Lecture
Challenging Retinal Detachments
Philip Ferrone, MD
9:03 ‒ 9:11 AMFour-Point Scleral-Fixation of Hydrophilic Acrylic
(Akreos A060) Lenses in Vitrectomized Eyes: A Retrospective
Analysis of Outcomes and Complications with Emphasis on
Intraocular Lens Opacification
Corrina Azarcon, MD
9:12 ‒ 9:20 AMEarly Experience with SeeLuma Visualization System
Flavio Rezende, MD
9:21 ‒ 9:29 AMMedical and Surgical Complications of Pathologic Myopia 
Gemmy Cheung, MD
9:29 ‒ 9:39 AMQ&A
9:45 ‒ 10:30 AMSATELLITE SYMPOSIUM
10:45 ‒ 11:10 AMBreak – Poster Session

PLENARY SESSION #3 – DRY AMD

11:15 ‒ 11:20 AMIntroduction to Session 3
11:20 ‒ 11:28 AMPachychoroid Spectrum Disorders – Current Understanding
Gemmy Cheung, MD
11:28 ‒ 11:33 AMQ&A
11:34 ‒ 11:42 AMA Prospective Longitudinal Study of Delayed Near InfraRed Analysis (DNIRA) Demonstrates Dynamic Changes of the Retinal Pigment Epithelium (RPE) in Non-Exudative Age-Related Macular Degeneration (AMD)
Geoff Williams, MD
11:43 – 11:51 AMFatty Acid Mimetics (FAMs) are a Novel Approach to the Treatment of Geographic Atrophy
Shelley Boyd, MD
11:52 AM –
12:00 PM
Pegcetacoplan vs. Avacincaptad Pegol in Geographic Atrophy: An Anchored Matching Adjusted Indirect Comparison ofThree Phase 3 Trials
Varun Chaudhary, MD
12:01 – 12:08 PMQ&A
12:09 – 12:17 PMStem Cell Derived Retinal Transplantation for Retinal Disease
Lyndon Da Cruz, MD, PhD
12:17 – 12:30 PMQ&A
12:30 PMLUNCH
1:30 – 2:15 PMSATELLITE SYMPOSIUM 

PLENARY SESSION #4 – WET AMD

2:35 – 2:40 PMIntroduction to Session 4
2:40 – 2:48 PMHD Eylea For Diabetic Macular Edema and Exudative Age-Related Macular Degeneration
Philip Ferrone, MD
2:48 – 2:53 PMQ&A
2:54 – 3:02 PMSubretinal Delivery of Investigational ABBV-RGX-314 for Neovascular Age-Related Macular Degeneration (nAMD): A Phase 2 Pharmacodynamic Study
Shaheer Aboobaker, MD
3:03 – 3:11 PMUnderstanding Macular Drusen: Are They All the Same?
Wai-Ching Lam, MD
3:12 – 3:17 PMQ&A 
3:18 – 3:26 PMPolypoidal Choroidal Vasculopathy – Evolution in Understanding and Management
Gemmy Cheung, MD
3:26 – 3:34 PMQ&A
3:35 – 4:20 PMSATELLITE SYMPOSIUM
4:20 – 5:10 PMBreak – Poster Session
5:15 – 6:00 PMCRS Annual General Meeting
6:30 PMGALA

Sunday, May 5, 2024

7:00 AM Breakfast

PLENARY SESSION #5 – DETACHMENTS

8:30 – 8:35 AMIntroduction to Session 5
8:35 – 8:43 AMProliferative Vitreoretinopathy in Rhegmatogenous Retinal Detachment Assessed with Swept-Source Optical Coherence Tomograph: A Novel Conceptual Framework
Isabela Martins Melo, MD
8:43 – 8:48 AMQ&A
8:49 – 8:57 AMPneumatic Retinopexy for Rhegmatogenous Retinal Detachment Associated with Giant Retinal Tears: Technique and Outcomes
Miguel Cruz-Pimentel, MD
8:58 – 9:06 AMArea Under the Curve Visual Acuity Following Rhegmatogenous Retinal Detachment Repair with Pneumatic Retinopexy vs Pars Plana Vitrectomy
Sue Ellen Demian, MD
9:06 – 9:12 AMQ&A

PLENARY SESSION #6 – AI AND THE RETINA

9:13 – 9:18 AMIntroduction to Section 6
9:18 – 9:26 AMThe Artificial Retina – Learning From the First Phase of Development and Products
Lyndon Da Cruz, MD
9:26 – 9:31 AMQ&A
9:32 – 9:40 AMArtificial Intelligence for Clinical Trials in Ophthalmology: Focus on Retinal Diseases
Stela Vujosevic, MD
9:40 – 9:45 AMQ&A
9:46 – 9:54 AMThe Role of Artificial Intelligence in Epiretinal Membrane and Macular Hole Management: A Scoping Review
Daniel Milad, MD
9:55 – 10:03 AMRetinal Fluid Analysis Using an Artificial Intelligence Convolutional Neural Network (CNN) in Optical Coherence Tomography (OCT) B-scans of Neo-Vascular Age-Related Macular Degeneration Study Eyes
Vlad Diaconita, MD
10:04 – 10:10 AMQ&A
10:10 – 10:30 AMBreak – Poster Session

PLENARY SESSION #7 – IMAGING UPDATE

10:35 – 10:40 AMIntroduction to Session 7
10:40 – 10:48 AMImaging Geographic Atrophy: Integrating Structure and Function to Better Understand the Effects of New Treatments
Stela Vujosevic, MD
10:50 – 10:58 AMPredictive Imaging Biomarkers in Diabetic Retinopathy
Varun Chaudhary, MD
10:59 – 11:07 AMAssessing Retinal Vascular Leakage with Optical Coherence Tomography Angiography (OCTA) and Deep Convolutional Neural Networks
Jovi Wong, MD
11:08 – 11:13 AMQ&A
11:14 – 11:22 AMMultimodal Imaging in Tractional Retinal Disorders
Lyndon Da Cruz, MD, PhD
11:24 – 11:32 AMMacular Function and Disorganization of Retinal Layers in Diabetic Retinopathy
Stela Vujosevic, MD
11:34 – 11:40 AMQ&A
11:40 – 11:48 AMMorphologic Stages of Full-Thickness Macular Hole Assessed with Spectral Domain Optical Coherence Tomography
Aurora Pecaku, MD
11:49 – 11:57 AMOptical Coherence Tomography Features in Fovea-Off Exudative Versus Rhegmatogenous Retinal Detachment
Paola Oquendo, MD
11:58 AM –
12:04 PM
Q&A
12:04 PMConcluding Remarks
Co-chairs: Bernard Hurley, MD, and Robert Gizicki, MD
12:20 PMLunch

Social Events

Welcome Reception

Friday, May 3, beginning at 6:00 PM

Cheers! Catch up with friends and colleagues at the Welcome Reception as we kick off the 2024 Canadian Retina Society Annual Meeting. 

Location: Fortifications, 9th Floor

*Please note that dress is business casual

Gala Reception and Dinner

Saturday, May 4, beginning at 6:30 PM

Location: Fortifications, 9th Floor

*Please note that dress is semi formal

Satellite Symposia

Bayer Symposium

Title: Advances in Retinal Disease Management

Date and time: Saturday, May 4 at 9:45‒10:30 AM

Keynote Speaker:

Ehsan Rahimy, MD
Director of Vitreoretinal Disease & Surgery, Palo Alto Medical Foundation
Adjunct Clinical Assistant Professor, Ophthalmology, Stanford University

Moderator:

John Galic, MD, FRCSC
Ophthalmologist, Specialist of Vitreoretinal Disease and Surgery
Centre universitaire de santé McGill et IR-CUSM l McGill University Health Centre and RI-MUHC

Panelists:

Varun Chaudhary, MD, FRCSC
Professor of Surgery, McMaster University
Hamilton Regional Eye Institute, St. Joseph’s Healthcare

Geoff Williams, MD, FRCSC
Associate Professor, University of Calgary
Medical Director of Southern Alberta Eye Clinic, Surgical

Overview:

The symposium will consist of a keynote presentation by Dr. Rahimy followed by a panel discussion with the Canadian faculty. For the keynote presentation Dr. Rahimy will review the current state of AMD and DME disease management highlighting the evolution of Anti-VEGF intravitreal treatments, challenges, and unmet needs faced by physicians and patients. Dr. Rahimy will then review some of the most recent data for aflibercept 8mg. The second part of the symposium will feature a panel discussion focusing on real-world patient cases from the US.

Learning Objectives: 

  • Understand the rationale of a higher molar dose of anti-VEGFs therapies newly approved in Canada
  • Review aflibercept 8mg 96-week clinical trial outcomes in nAMD & DME treatment  
  • Discuss real-world case presentation

Apellis Symposium

Title: Eyes on GA: Expert Insights on a New Era of Management

Date and time: Saturday, May 4 at 1:30‒2:15 PM

Overview:

Geographic atrophy remains a significant unmet medical need in Canada. This symposium aims to advance geographic atrophy knowledge and awareness in the Canadian retina community and explore emerging therapies in the treatment landscape.

Objectives

  1. Geographic Atrophy (GA): Educate on the role of multimodal imaging to diagnose GA and identify risk markers for progression.
  2. Efficacy and safety of complement inhibition in GA: Share recent analyses from complement inhibitors studies, including 3-year treatment data.
  3. Structural and functional analyses of interest in GA: Discuss the relationship between anatomical and functional outcomes.
  4. Real-world experience with complement inhibitors

Faculty

  • Moderator:  Deepa Yoganathan, MD
  • Speakers:  Phil Ferrone, MD; Bernard Hurley, MD

Roche Symposium

Title: Optimizing nAMD and DME Management: Leveraging Fluid Dynamics for Functional Improvement

Date and time: Saturday, May 4 at 3:35‒4:20 PM

Learning Objectives:

  • Differentiate various classes of anti-vascular endothelial growth factor drugs and other therapeutic options for nAMD, considering their respective impact on both anatomical and functional outcomes.
  • Assess new evidence about treatments for DME that maximize vision gains and minimize macular leakage.

Faculty

  • Chair: Varun Chaudhary, MD
  • Arshad Khanani, MD
  • Stela Vujosevic, MD, PhD, FARVO, FEBO

Annual Meeting Agenda

All Sessions: Cinema - Ground Floor

Note: this meeting will take place in English.

Guest Speakers:

Robyn Guymer, AM, MBBS, PhD, FRANZCO, FAHMS
Professor of Ophthalmology
Melbourne University
Deputy Director
Centre for Eye Research Australia
Melbourne, Victoria, Australia
Sobha Sivaprasad, MBBS, FRCS, FRCOphth
Medical Retina Consultant Ophthalmologist
Moorfields Eye Hospital NHS Foundation Trust
Professor in Retinal Clinical Research
University College London
London, United Kingdom
Carl D. Regillo, MD, FASRS
Professor of Ophthalmology
Thomas Jefferson University
Chief, Retina Service, and Founder
Wills Eye Clinical Retina Research Unit, Wills Eye Hospital
Sunil K. Srivastava, MD
Staff Physician
Cole Eye Institute, Cleveland Clinic
Cleveland, Ohio

Friday, May 12

PLENARY SESSION #1COAST-TO-COAST RETINA CHECKUP PART 1 SURGERY
Moderators: Bernard Hurley, MD, and Robert Gizicki, MD

3:30 pm Welcome and Opening Remarks

3:40 pm Vitreoretinal Surgical Video Session: “Masters of Disasters”
David Wong, MD
Q&A (included)

4:25 pm Vitreoretinal Surgery in Uveitis
Sunil Srivastava, MD

4:40 pm  Q&A Session

4:45 pm Pearls in Pediatric Retina Surgery
Cynthia Qian, MD

4:51 pm Complex Vitreoretinal Surgery
Flavio Rezende, MD, PhD

4:57 pm Bacillary Layer Detachment in the Pathophysiology of Secondary Macular Hole in Fovea-off Rhegmatogenous Retinal Detachment
Isabela M. Melo, MD

5:03 pm Q&A

5:11 pm Efficacy and Safety of Proposed MYL-1701P Biosimilar Compared to Eylea® (Reference Aflibercept) in Diabetic Macular Edema: A Randomized, Double-masked, Phase 3 Equivalence Study (INSIGHT Study)
Susan B. Bressler, MD

5:17 pm 2-Year Evaluation of Subretinal Fluid Drainage Techniques in Pars Plana Vitrectomy for Primary Rhegmatogenous Retinal Detachment
(ELLIPSOID-2 Study)
Aditya Bansal, MD

5:23 pm Lenses for Pars Plana Scleral Fixation
Amar Mannina, MD

5:29 pm Q&A

5:37 pm Session 1 Concluding Remarks
Moderators: Bernard Hurley, MD, and Robert Gizicki, MD

6:00 pm Welcome Reception - Princes' Gates Ballroom

Saturday, May 13

7:00 am BREAKFAST – Princes’ Gates Ballroom

7:30 am SATELLITE SYMPOSIUM – Cinema Ground Floor

PLENARY SESSION #2 – AGE-RELATED MACULAR DEGENERATION & DIABETIC MACULAR EDEMA
Moderators: Varun Chaudhary, MD, and Jason Noble, MD

8:30 am Introduction to Section 2

8:40 am Reticular Pseudodrusen – A Critical Phenotype
Robyn Guymer, AM, PhD

8:55 am Q&A

9:02 am Tyrosine Kinase Inhibition for nAMD Clinical Trial Studies
Carl Regillo, MD

9:17 am Q&A

9:24 am Early OCT Signs of Atrophy in AMD
Robyn Guymer, AM, PhD

9:39 am Q&A

9:46 am Translating Clinical Trials to Practice in Geographic Atrophy
Sobha Sivaprasad, MBBS

10:01 am Q&A

10:08 am VOYAGER: An Innovative Real-world Study of Faricimab and the Port Delivery System with Ranibizumab in Patients with nAMD and DME
Robyn Guymer, AM, PhD

10:23 am Q&A

10:30 am BREAK – Princes’ Gates Ballroom Pre-function Area, 3rd Floor
Poster Session

 

PLENARY SESSION #3 – Retinal Vascular Disease
Moderators: Bernard Hurley, MD, and Robert Gizicki, MD

11:00 am Introduction to Session 3

11:05 am Choice of Agent in CRVO
Sobha Sivaprasad, MBBS

11:15 am Q&A

11:22 am CRAO Management and CRAO Masquerades
Sunil Srivastava, MD

11:37 am Q&A

11:44 am Where Do We Place Biosimilars in Our DME Treatment Algorithm?
Sobha Sivaprasad, MBBS

12:00 pm Q&A

12:07 pm Discontinuous Versus Continuous Treatment for DME: Evidence Review and Evidence Generation
Varun Chaudhary, MD

12:22 pm Q&A

12:30 pm LUNCH – Princes’ Gates Ballroom

1:15 pm SATELLITE SYMPOSIUM – Cinema Ground Floor

 

PLENARY SESSION #4 – Surgery
Moderator: Bernard Hurley, MD, and Wai-Ching Lam, MD

2:15 pm Introduction to Session 4

2:20 pm Perfluorocarbon Liquid in Retinal Detachment Repair: Pearls and Pitfalls
Carl Regillo, MD

2:35 pm Q&A

2:42 pm Mila Oh Memorial Lecture: Diagnosis and Management of Diabetic Retinopathy in 2030
Sobha Sivaprasad, MBBS

2:57 pm Q&A

3:04 pm The Surgical Management of Inherited Retinal Diseases
Peter Kertes, MD

3:19 pm Q&A

3:26 pm Gene Therapy for Neovascular AMD and Diabetic Retinopathy
Carl Regillo, MD

3:41 pm Q&A

3:48 pm BREAK – Princes’ Gates Ballroom Pre-function Area, 3rd Floor
Poster Session

 

PLENARY SESSION #5 – Uveitis
Moderators: Phil Hooper, MD, and Robert Gizicki, MD

4:15 pm Introduction to Session 5

4:25 pm Masquerade Syndromes, New Treatment in Uveitis Imaging
Sunil Srivastava, MD

4:40 pm Q&A

4:47 pm Clinical and Imaging Pearls in Uveitis
Nupura Bakshi, MD

5:02 pm Q&A

5:15-6:00 pm CRS Annual General Meeting – Cinema Ground Floor

6:30 pm GALA – Princes’ Gates Ballroom

Sunday, May 14

7:30 am BREAKFAST

PLENARY SESSION #6 – Coast-to-Coast Part 2 Medical Retina
Moderators: Bernard Hurley, MD, and Robert Gizicki, MD

8:45 am Introduction to Session 6

8:50 am Pachychoroid Spectrum Diseases
Wai-Ching Lam, MD

8:56 am Scleral Buckle Techniques
Geoff Williams, MD

9:02 am Exciting and New
Mark Greve, MD

9:08 am Does Anti-VEGF Treatment Impact Retinal Nonperfusion in Diabetic Retinopathy?
Varun Chaudhary, MD

9:14 am Q&A

9:30 am SPONSORED SYMPOSIUM – Cinema Ground Floor

10:30 am BREAK – Trillium Park Studio, 3rd Floor
Poster Session

10:45 am Assessment of Geographic Atrophy Progression in the Phase 3 OAKS and DERBY Trials
Tom Sheidow, MD

10:51 am Retinal Displacement After Scleral Buckle Versus Combined Buckle and Vitrectomy for Rhegmatogenous Retina Detachment: ALIGN SB vs PPV-SB
Aditya Bansal, MD

10:57 am The Long-term Structural and Functional Impact of Retinopathy of Prematurity
Cynthia Qian, MD

11:03 am Delayed Near InfraRed Analysis (DNIRA) Identifies Novel Features of Nonexudative (Dry) AMD in a Prospective, Natural History Study
Filiberto Altomare, MD

11:09 am Q&A

11:24 am Concluding Remarks
Co-chairs: Bernard Hurley, MD, and Robert Gizicki, MD

12:00 pm LUNCH – Princes’ Gates Ballroom

Poster Presenters

Isabela M. Melo, MD – Toronto, ON

  • Posterior Hyaloid Discontinuity on Optical Coherence Tomography in Partial Posterior Vitreous Detachment and Vitreomacular Traction
  • Impact of Baseline Morphological Stage on Post-operative Outcomes in Rhegmatogenous Retinal Detachment

Parnian Arjmand, MD – Toronto, ON

  • Juxtafoveal Retinal Arterial Macroaneurysm: The Role of Ancillary Imaging

Amin Kherani, MD – Calgary, AB

  • Intraocular foreign body injuries from a Calgary perspective – a retrospective case series

Carl Shen, MD – Hamilton, ON

  • Intraretinal silicone oil migration: An under recognized OCT phenotype

Paola Oquendo, MD – Hamilton, ON

  • Comparison of the Photoreceptor Mosaic Before and After Macular Hole Surgery with High Resolution Adaptive Optics Imaging
  • Epiretinal Membrane and Associated Tractional Abnormalities Following Rhegmatogenous Retinal Detachment Repair

Hatim Batawi, MD – Toronto, ON

  • Outer Retinal Hyperreflective Dots, A Potential Biomarker in Rhegmatogenous Retinal Detachment

Khaldon Abbas – Vancouver, BC

  • Characteristics of No-show appointments at a multicenter retina subspeciality practice

Aurora Pecaku, MD – Toronto, ON

  • Reattachment Rate with Pneumatic Retinopexy vs Pars Plana Vitrectomy for Rhegmatogenous Retinal Detachment with a Single Break in Detached Retina Only

Irina Sverdlichenko – Toronto, ON

  • Macular Hole Associated Retinal Detachment in High Myopic Patients: Case series and Overview of a Novel Surgical Technique

Aaditeya Jhaveri – Toronto, ON

  • Optical coherence tomography biomarkers as potential predictors for visual function and response to intravitreal therapy in diabetic macular edema: a review

Fowad Daud – Hamilton, ON

  • Combined versus Sequential Pars Plana Vitrectomy and Phacoemulsification for Macular Hole and Epiretinal Membrane – A Systematic Review and Meta-Analysis

Milena Cioana – Toronto, ON

  • Post-procedural endophthalmitis visual outcomes by microorganism: A systematic review and meta-analysis
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