Satellite Symposia

Astellas

Title: Advancements in Geographic Atrophy

Objectives:
1. Understand the most recent findings regarding the underlying mechanisms that lead to the development of GA secondary to AMD
2. Explain the rationale for early diagnosis of GA secondary to AMD and the significance of the latest imaging technologies for timely detection and monitoring of disease progression
3. Review of the latest evidence-based medicine & clinical pearls when managing patients with GA secondary to AMD

Faculty:
1. Dr. Rishi Singh, MD (Speaker)
2. Dr. David Sarraf, MD (Speaker – TBD)
3. Dr. Varun Chaudhary, MD (Moderator)
4. Dr. Shelley Boyd, MD (Panelist)

Apotex

Title: Biosimilars in Retinal Disease

Objectives:

After participating in this symposium, CRS delegates will be better able to:

Appreciate the rationale for biosimilars in Canada’s healthcare system
Understand the regulatory process for biosimilar evaluation and approval
Evaluate trial results of biosimilars in retinal disease

Faculty:

Dr. Bernard Hurley, MD (Moderator)
Dr. Rishi Singh, MD (Speaker)
Dr. David Brown, MD (Speaker)

Bayer: More info to follow

Roche: More info to follow

Bayer Symposium

Title: Advances in Retinal Disease Management

Date and time: Saturday, May 4 at 9:45‒10:30 AM

Keynote Speaker:

Ehsan Rahimy, MD
Director of Vitreoretinal Disease & Surgery, Palo Alto Medical Foundation
Adjunct Clinical Assistant Professor, Ophthalmology, Stanford University

Moderator:

John Galic, MD, FRCSC
Ophthalmologist, Specialist of Vitreoretinal Disease and Surgery
Centre universitaire de santé McGill et IR-CUSM l McGill University Health Centre and RI-MUHC

Panelists:

Varun Chaudhary, MD, FRCSC
Professor of Surgery, McMaster University
Hamilton Regional Eye Institute, St. Joseph’s Healthcare

Geoff Williams, MD, FRCSC
Associate Professor, University of Calgary
Medical Director of Southern Alberta Eye Clinic, Surgical

Overview:

The symposium will consist of a keynote presentation by Dr. Rahimy followed by a panel discussion with the Canadian faculty. For the keynote presentation Dr. Rahimy will review the current state of AMD and DME disease management highlighting the evolution of Anti-VEGF intravitreal treatments, challenges, and unmet needs faced by physicians and patients. Dr. Rahimy will then review some of the most recent data for aflibercept 8mg. The second part of the symposium will feature a panel discussion focusing on real-world patient cases from the US.

Learning Objectives:

Understand the rationale of a higher molar dose of anti-VEGFs therapies newly approved in Canada
Review aflibercept 8mg 96-week clinical trial outcomes in nAMD & DME treatment
Discuss real-world case presentation

Apellis Symposium

Title: Eyes on GA: Expert Insights on a New Era of Management

Date and time: Saturday, May 4 at 1:30‒2:15 PM

Overview:

Geographic atrophy remains a significant unmet medical need in Canada. This symposium aims to advance geographic atrophy knowledge and awareness in the Canadian retina community and explore emerging therapies in the treatment landscape.

Objectives

Geographic Atrophy (GA): Educate on the role of multimodal imaging to diagnose GA and identify risk markers for progression.
Efficacy and safety of complement inhibition in GA: Share recent analyses from complement inhibitors studies, including 3-year treatment data.
Structural and functional analyses of interest in GA: Discuss the relationship between anatomical and functional outcomes.
Real-world experience with complement inhibitors

Faculty

Moderator: Deepa Yoganathan, MD
Speakers: Phil Ferrone, MD; Bernard Hurley, MD

Roche Symposium

Title: Optimizing nAMD and DME Management: Leveraging Fluid Dynamics for Functional Improvement

Date and time: Saturday, May 4 at 3:35‒4:20 PM

Learning Objectives:

Differentiate various classes of anti-vascular endothelial growth factor drugs and other therapeutic options for nAMD, considering their respective impact on both anatomical and functional outcomes.
Assess new evidence about treatments for DME that maximize vision gains and minimize macular leakage.

Faculty

Chair: Varun Chaudhary, MD
Arshad Khanani, MD
Stela Vujosevic, MD, PhD, FARVO, FEBO

Annual Meeting Agenda

All Sessions: Cinema - Ground Floor

Note: this meeting will take place in English.

Guest Speakers:

Robyn Guymer, AM, MBBS, PhD, FRANZCO, FAHMS
Professor of Ophthalmology
Melbourne University
Deputy Director
Centre for Eye Research Australia
Melbourne, Victoria, Australia

Sobha Sivaprasad, MBBS, FRCS, FRCOphth
Medical Retina Consultant Ophthalmologist
Moorfields Eye Hospital NHS Foundation Trust
Professor in Retinal Clinical Research
University College London
London, United Kingdom

Carl D. Regillo, MD, FASRS
Professor of Ophthalmology
Thomas Jefferson University
Chief, Retina Service, and Founder
Wills Eye Clinical Retina Research Unit, Wills Eye Hospital

Sunil K. Srivastava, MD
Staff Physician
Cole Eye Institute, Cleveland Clinic
Cleveland, Ohio

Friday, May 12

PLENARY SESSION #1 – COAST-TO-COAST RETINA CHECKUP PART 1 SURGERY
Moderators: Bernard Hurley, MD, and Robert Gizicki, MD

3:30 pm Welcome and Opening Remarks

3:40 pm Vitreoretinal Surgical Video Session: “Masters of Disasters”
David Wong, MD
Q&A (included)

4:25 pm Vitreoretinal Surgery in Uveitis
Sunil Srivastava, MD

4:40 pm Q&A Session

4:45 pm Pearls in Pediatric Retina Surgery
Cynthia Qian, MD

4:51 pm Complex Vitreoretinal Surgery
Flavio Rezende, MD, PhD

4:57 pm Bacillary Layer Detachment in the Pathophysiology of Secondary Macular Hole in Fovea-off Rhegmatogenous Retinal Detachment
Isabela M. Melo, MD

5:03 pm Q&A

5:11 pm Efficacy and Safety of Proposed MYL-1701P Biosimilar Compared to Eylea® (Reference Aflibercept) in Diabetic Macular Edema: A Randomized, Double-masked, Phase 3 Equivalence Study (INSIGHT Study)
Susan B. Bressler, MD

5:17 pm 2-Year Evaluation of Subretinal Fluid Drainage Techniques in Pars Plana Vitrectomy for Primary Rhegmatogenous Retinal Detachment
(ELLIPSOID-2 Study)
Aditya Bansal, MD

5:23 pm Lenses for Pars Plana Scleral Fixation
Amar Mannina, MD

5:29 pm Q&A

5:37 pm Session 1 Concluding Remarks
Moderators: Bernard Hurley, MD, and Robert Gizicki, MD

6:00 pm Welcome Reception - Princes' Gates Ballroom

Saturday, May 13

7:00 am BREAKFAST – Princes’ Gates Ballroom

7:30 am SATELLITE SYMPOSIUM – Cinema Ground Floor

PLENARY SESSION #2 – AGE-RELATED MACULAR DEGENERATION & DIABETIC MACULAR EDEMA
Moderators: Varun Chaudhary, MD, and Jason Noble, MD

8:30 am Introduction to Section 2

8:40 am Reticular Pseudodrusen – A Critical Phenotype
Robyn Guymer, AM, PhD

8:55 am Q&A

9:02 am Tyrosine Kinase Inhibition for nAMD Clinical Trial Studies
Carl Regillo, MD

9:17 am Q&A

9:24 am Early OCT Signs of Atrophy in AMD
Robyn Guymer, AM, PhD

9:39 am Q&A

9:46 am Translating Clinical Trials to Practice in Geographic Atrophy
Sobha Sivaprasad, MBBS

10:01 am Q&A

10:08 am VOYAGER: An Innovative Real-world Study of Faricimab and the Port Delivery System with Ranibizumab in Patients with nAMD and DME
Robyn Guymer, AM, PhD

10:23 am Q&A

10:30 am BREAK – Princes’ Gates Ballroom Pre-function Area, 3^rd Floor
Poster Session

PLENARY SESSION #3 – Retinal Vascular Disease
Moderators: Bernard Hurley, MD, and Robert Gizicki, MD

11:00 am Introduction to Session 3

11:05 am Choice of Agent in CRVO
Sobha Sivaprasad, MBBS

11:15 am Q&A

11:22 am CRAO Management and CRAO Masquerades
Sunil Srivastava, MD

11:37 am Q&A

11:44 am Where Do We Place Biosimilars in Our DME Treatment Algorithm?
Sobha Sivaprasad, MBBS

12:00 pm Q&A

12:07 pm Discontinuous Versus Continuous Treatment for DME: Evidence Review and Evidence Generation
Varun Chaudhary, MD

12:22 pm Q&A

12:30 pm LUNCH – Princes’ Gates Ballroom

1:15 pm SATELLITE SYMPOSIUM – Cinema Ground Floor

PLENARY SESSION #4 – Surgery
Moderator: Bernard Hurley, MD, and Wai-Ching Lam, MD

2:15 pm Introduction to Session 4

2:20 pm Perfluorocarbon Liquid in Retinal Detachment Repair: Pearls and Pitfalls
Carl Regillo, MD

2:35 pm Q&A

2:42 pm Mila Oh Memorial Lecture: Diagnosis and Management of Diabetic Retinopathy in 2030
Sobha Sivaprasad, MBBS

2:57 pm Q&A

3:04 pm The Surgical Management of Inherited Retinal Diseases
Peter Kertes, MD

3:19 pm Q&A

3:26 pm Gene Therapy for Neovascular AMD and Diabetic Retinopathy
Carl Regillo, MD

3:41 pm Q&A

3:48 pm BREAK – Princes’ Gates Ballroom Pre-function Area, 3^rd Floor
Poster Session

PLENARY SESSION #5 – Uveitis
Moderators: Phil Hooper, MD, and Robert Gizicki, MD

4:15 pm Introduction to Session 5

4:25 pm Masquerade Syndromes, New Treatment in Uveitis Imaging
Sunil Srivastava, MD

4:40 pm Q&A

4:47 pm Clinical and Imaging Pearls in Uveitis
Nupura Bakshi, MD

5:02 pm Q&A

5:15-6:00 pm CRS Annual General Meeting – Cinema Ground Floor

6:30 pm GALA – Princes’ Gates Ballroom

Sunday, May 14

7:30 am BREAKFAST

PLENARY SESSION #6 – Coast-to-Coast Part 2 Medical Retina
Moderators: Bernard Hurley, MD, and Robert Gizicki, MD

8:45 am Introduction to Session 6

8:50 am Pachychoroid Spectrum Diseases
Wai-Ching Lam, MD

8:56 am Scleral Buckle Techniques
Geoff Williams, MD

9:02 am Exciting and New
Mark Greve, MD

9:08 am Does Anti-VEGF Treatment Impact Retinal Nonperfusion in Diabetic Retinopathy?
Varun Chaudhary, MD

9:14 am Q&A

9:30 am SPONSORED SYMPOSIUM – Cinema Ground Floor

10:30 am BREAK – Trillium Park Studio, 3^rd Floor
Poster Session

10:45 am Assessment of Geographic Atrophy Progression in the Phase 3 OAKS and DERBY Trials
Tom Sheidow, MD

10:51 am Retinal Displacement After Scleral Buckle Versus Combined Buckle and Vitrectomy for Rhegmatogenous Retina Detachment: ALIGN SB vs PPV-SB
Aditya Bansal, MD

10:57 am The Long-term Structural and Functional Impact of Retinopathy of Prematurity
Cynthia Qian, MD

11:03 am Delayed Near InfraRed Analysis (DNIRA) Identifies Novel Features of Nonexudative (Dry) AMD in a Prospective, Natural History Study
Filiberto Altomare, MD

11:09 am Q&A

11:24 am Concluding Remarks
Co-chairs: Bernard Hurley, MD, and Robert Gizicki, MD

12:00 pm LUNCH – Princes’ Gates Ballroom

Poster Presenters

Isabela M. Melo, MD – Toronto, ON

Posterior Hyaloid Discontinuity on Optical Coherence Tomography in Partial Posterior Vitreous Detachment and Vitreomacular Traction
Impact of Baseline Morphological Stage on Post-operative Outcomes in Rhegmatogenous Retinal Detachment

Parnian Arjmand, MD – Toronto, ON

Juxtafoveal Retinal Arterial Macroaneurysm: The Role of Ancillary Imaging

Amin Kherani, MD – Calgary, AB

Intraocular foreign body injuries from a Calgary perspective – a retrospective case series

Carl Shen, MD – Hamilton, ON

Intraretinal silicone oil migration: An under recognized OCT phenotype

Paola Oquendo, MD – Hamilton, ON

Comparison of the Photoreceptor Mosaic Before and After Macular Hole Surgery with High Resolution Adaptive Optics Imaging
Epiretinal Membrane and Associated Tractional Abnormalities Following Rhegmatogenous Retinal Detachment Repair

Hatim Batawi, MD – Toronto, ON

Outer Retinal Hyperreflective Dots, A Potential Biomarker in Rhegmatogenous Retinal Detachment

Khaldon Abbas – Vancouver, BC

Characteristics of No-show appointments at a multicenter retina subspeciality practice

Aurora Pecaku, MD – Toronto, ON

Reattachment Rate with Pneumatic Retinopexy vs Pars Plana Vitrectomy for Rhegmatogenous Retinal Detachment with a Single Break in Detached Retina Only

Irina Sverdlichenko – Toronto, ON

Macular Hole Associated Retinal Detachment in High Myopic Patients: Case series and Overview of a Novel Surgical Technique

Aaditeya Jhaveri – Toronto, ON

Optical coherence tomography biomarkers as potential predictors for visual function and response to intravitreal therapy in diabetic macular edema: a review

Fowad Daud – Hamilton, ON

Combined versus Sequential Pars Plana Vitrectomy and Phacoemulsification for Macular Hole and Epiretinal Membrane – A Systematic Review and Meta-Analysis

Milena Cioana – Toronto, ON

Post-procedural endophthalmitis visual outcomes by microorganism: A systematic review and meta-analysis